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A Comparative Study of Conventional Wound Irrigants and Their Effectiveness in Wound Healing

Original articles


Debridement is essential for wound healing. It accelerates the normal process of wound healing if done properly. Wound irrigation helps to achieve wound hydration, removes deeper debris, and assists in visual examination of the wound. This  study aimed  to investigate and  compare the utility, complication rates,  and outcome of  chemical wound  debridement  with  different  agents  commonly  used  as   irrigants viz. sterile water, normal saline (NS), povidone iodine (PI), hydrogen peroxide (H2O2), hypochlorite and neutralized  superoxidised solution of water (nSOS). In  contaminated  wounds  with  co morbid  factors  nSOS  remained   the  irrigant  of  choice  followed  by  H2O2  and  PI. Hypochlorite gave   good results in wounds where repeated debridement was required.  However,  normal  saline  and  sterile  water  came  up  to  be  poor  quality  irrigants  with  high  complication  rates  in  dirty  or  contaminated wounds.