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Are Generic Anti-infectives Effective?


Generic products have been defined as “a drug product that is comparable to brand/reference listed drug product in dosage form, strength, route of administration, quality and performance characteristics, and intended use.” They are usually produced after the patent held by the manufacturer of the innovator product has expired.

Drug efficacy is directly related to the achievement of suitable concentrations of the drug at the target tissue and for most orally administered drugs the target is the plasma. In the last 3 decades or so, the concept of bioequivalence has been accepted as indicative of equivalence in therapeutic efficacy of 2 products.